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Aberrant DNA methylation of cancer-related genes in giant breast fibroadenoma: a case report

INTRODUCTION: Giant fibroadenoma is an uncommon variant of benign breast lesions. Aberrant methylation of CpG islands in promoter regions is known to be involved in the silencing of genes (for example, tumor-suppressor genes) and appears to be an early event in the etiology of breast carcinogenesis....

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Detalles Bibliográficos
Autores principales: Marzese, Diego M, Gago, Francisco E, Orozco, Javier I, Tello, Olga M, Roqué, María, Vargas-Roig, Laura M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206866/
https://www.ncbi.nlm.nih.gov/pubmed/22011321
http://dx.doi.org/10.1186/1752-1947-5-516