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Aberrant DNA methylation of cancer-related genes in giant breast fibroadenoma: a case report
INTRODUCTION: Giant fibroadenoma is an uncommon variant of benign breast lesions. Aberrant methylation of CpG islands in promoter regions is known to be involved in the silencing of genes (for example, tumor-suppressor genes) and appears to be an early event in the etiology of breast carcinogenesis....
Autores principales: | Marzese, Diego M, Gago, Francisco E, Orozco, Javier I, Tello, Olga M, Roqué, María, Vargas-Roig, Laura M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206866/ https://www.ncbi.nlm.nih.gov/pubmed/22011321 http://dx.doi.org/10.1186/1752-1947-5-516 |
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