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The Circadian Deadenylase Nocturnin Is Necessary for Stabilization of the iNOS mRNA in Mice

Nocturnin is a member of the CCR4 deadenylase family, and its expression is under circadian control with peak levels at night. Because it can remove poly(A) tails from mRNAs, it is presumed to play a role in post-transcriptional control of circadian gene expression, but its target mRNAs are not know...

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Detalles Bibliográficos
Autores principales: Niu, Shuang, Shingle, Danielle L., Garbarino-Pico, Eduardo, Kojima, Shihoko, Gilbert, Misty, Green, Carla B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206874/
https://www.ncbi.nlm.nih.gov/pubmed/22073225
http://dx.doi.org/10.1371/journal.pone.0026954