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Impact of MUC1 Mucin Downregulation in the Phenotypic Characteristics of MKN45 Gastric Carcinoma Cell Line

BACKGROUND: Gastric carcinoma is the second leading cause of cancer-associated death worldwide. The high mortality associated with this disease is in part due to limited knowledge about gastric carcinogenesis and a lack of available therapeutic and prevention strategies. MUC1 is a high molecular wei...

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Detalles Bibliográficos
Autores principales: Costa, Natália R., Paulo, Paula, Caffrey, Thomas, Hollingsworth, Michael A., Santos-Silva, Filipe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206881/
https://www.ncbi.nlm.nih.gov/pubmed/22073229
http://dx.doi.org/10.1371/journal.pone.0026970