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Local Genealogies in a Linear Mixed Model for Genome-Wide Association Mapping in Complex Pedigreed Populations

INTRODUCTION: The state-of-the-art for dealing with multiple levels of relationship among the samples in genome-wide association studies (GWAS) is unified mixed model analysis (MMA). This approach is very flexible, can be applied to both family-based and population-based samples, and can be extended...

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Detalles Bibliográficos
Autores principales: Sahana, Goutam, Mailund, Thomas, Lund, Mogens Sandø, Guldbrandtsen, Bernt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206889/
https://www.ncbi.nlm.nih.gov/pubmed/22073255
http://dx.doi.org/10.1371/journal.pone.0027061