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Local Genealogies in a Linear Mixed Model for Genome-Wide Association Mapping in Complex Pedigreed Populations
INTRODUCTION: The state-of-the-art for dealing with multiple levels of relationship among the samples in genome-wide association studies (GWAS) is unified mixed model analysis (MMA). This approach is very flexible, can be applied to both family-based and population-based samples, and can be extended...
Autores principales: | Sahana, Goutam, Mailund, Thomas, Lund, Mogens Sandø, Guldbrandtsen, Bernt |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206889/ https://www.ncbi.nlm.nih.gov/pubmed/22073255 http://dx.doi.org/10.1371/journal.pone.0027061 |
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