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N-Glycosylation of ß4 Integrin Controls the Adhesion and Motility of Keratinocytes

α6ß4 integrin is an essential component of hemidesmosomes and modulates cell migration in wound healing and cancer invasion. To elucidate the role of N-glycosylation on ß4 integrin, we investigated keratinocyte adhesion and migration through the re-expression of wild-type or N-glycosylation-defectiv...

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Detalles Bibliográficos
Autores principales: Kariya, Yoshinobu, Gu, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206902/
https://www.ncbi.nlm.nih.gov/pubmed/22073258
http://dx.doi.org/10.1371/journal.pone.0027084