Rad51 and BRCA2 - New Molecular Targets for Sensitizing Glioma Cells to Alkylating Anticancer Drugs

First line chemotherapeutics for brain tumors (malignant gliomas) are alkylating agents such as temozolomide and nimustine. Despite growing knowledge of how these agents work, patients suffering from this malignancy still face a dismal prognosis. Alkylating agents target DNA, forming the killing les...

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Detalles Bibliográficos
Autores principales: Quiros, Steve, Roos, Wynand Paul, Kaina, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206939/
https://www.ncbi.nlm.nih.gov/pubmed/22073281
http://dx.doi.org/10.1371/journal.pone.0027183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206939/
https://www.ncbi.nlm.nih.gov/pubmed/22073281
http://dx.doi.org/10.1371/journal.pone.0027183

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