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Intravenous KITENIN shRNA Injection Suppresses Hepatic Metastasis and Recurrence of Colon Cancer in an Orthotopic Mouse Model

KITENIN (KAI1 C-terminal interacting tetraspanin) promotes invasion and metastasis in mouse colon cancer models. In the present study, we evaluated the effects of KITENIN knockdown by intravenous administration of short hairpin RNAs (shRNAs) in an orthotopic mouse colon cancer model, simulating a pr...

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Detalles Bibliográficos
Autores principales: Hwang, Jun-Eul, Shim, Hyun-Jeong, Park, Young-Kyu, Cho, Sang-Hee, Bae, Woo-Kyun, Kim, Dae-Eun, Kim, Kyung-Keun, Chung, Ik-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207046/
https://www.ncbi.nlm.nih.gov/pubmed/22065899
http://dx.doi.org/10.3346/jkms.2011.26.11.1439