Cargando…

ROCKing Regeneration: Rho Kinase Inhibition as Molecular Target for Neurorestoration

Regenerative failure in the CNS largely depends on pronounced growth inhibitory signaling and reduced cellular survival after a lesion stimulus. One key mediator of growth inhibitory signaling is Rho-associated kinase (ROCK), which has been shown to modulate growth cone stability by regulation of ac...

Descripción completa

Detalles Bibliográficos
Autores principales: Tönges, Lars, Koch, Jan-Christoph, Bähr, Mathias, Lingor, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207219/
https://www.ncbi.nlm.nih.gov/pubmed/22065949
http://dx.doi.org/10.3389/fnmol.2011.00039