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ROCKing Regeneration: Rho Kinase Inhibition as Molecular Target for Neurorestoration
Regenerative failure in the CNS largely depends on pronounced growth inhibitory signaling and reduced cellular survival after a lesion stimulus. One key mediator of growth inhibitory signaling is Rho-associated kinase (ROCK), which has been shown to modulate growth cone stability by regulation of ac...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Research Foundation
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207219/ https://www.ncbi.nlm.nih.gov/pubmed/22065949 http://dx.doi.org/10.3389/fnmol.2011.00039 |