Cargando…

GRK5 promotes F-actin bundling and targets bundles to membrane structures to control neuronal morphogenesis

Neuronal morphogenesis requires extensive membrane remodeling and cytoskeleton dynamics. In this paper, we show that GRK5, a G protein–coupled receptor kinase, is critically involved in neurite outgrowth, dendrite branching, and spine morphogenesis through promotion of filopodial protrusion. Interes...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yuejun, Wang, Feifei, Long, Hui, Chen, Ying, Wu, Ziyan, Ma, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207290/
https://www.ncbi.nlm.nih.gov/pubmed/21930777
http://dx.doi.org/10.1083/jcb.201104114