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Impact of Changing Drug Treatment and Malaria Endemicity on the Heritability of Malaria Phenotypes in a Longitudinal Family-Based Cohort Study

Despite considerable success of genome wide association (GWA) studies in identifying causal variants for many human diseases, their success in unraveling the genetic basis to complex diseases has been more mitigated. Pathogen population structure may impact upon the infectious phenotype, especially...

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Detalles Bibliográficos
Autores principales: Loucoubar, Cheikh, Goncalves, Bronner, Tall, Adama, Sokhna, Cheikh, Trape, Jean-François, Diène Sarr, Fatoumata, Faye, Joseph, Badiane, Abdoulaye, Ly, Alioune Badara, Diop, Aliou, Bar-Hen, Avner, Bureau, Jean-François, Sakuntabhai, Anavaj, Paul, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207815/
https://www.ncbi.nlm.nih.gov/pubmed/22073159
http://dx.doi.org/10.1371/journal.pone.0026364