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Characterization of the Estradiol-Binding Site Structure of Human Protein Disulfide Isomerase (PDI)
BACKGROUND: Earlier studies showed that 17β-estradiol (E(2)), an endogenous female sex hormone, can bind to human protein disulfide isomerase (PDI), a protein folding catalyst for disulfide bond formation and rearrangement. This binding interaction can modulate the intracellular levels of E(2) and i...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207843/ https://www.ncbi.nlm.nih.gov/pubmed/22073283 http://dx.doi.org/10.1371/journal.pone.0027185 |