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Characterization of the Estradiol-Binding Site Structure of Human Protein Disulfide Isomerase (PDI)

BACKGROUND: Earlier studies showed that 17β-estradiol (E(2)), an endogenous female sex hormone, can bind to human protein disulfide isomerase (PDI), a protein folding catalyst for disulfide bond formation and rearrangement. This binding interaction can modulate the intracellular levels of E(2) and i...

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Detalles Bibliográficos
Autores principales: Fu, Xin-Miao, Wang, Pan, Zhu, Bao Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207843/
https://www.ncbi.nlm.nih.gov/pubmed/22073283
http://dx.doi.org/10.1371/journal.pone.0027185