A Switch from Canonical to Noncanonical Wnt Signaling Mediates Drug Resistance in Colon Cancer Cells

Butyrate, a fermentation product of fiber in the colon, acts as a histone deacetylase inhibitor (HDACi) and induces apoptosis in colon cancer (CC) cells in vitro. We have reported that the apoptotic effects of butyrate are dependent upon the hyperactivation of the Wnt/beta-catenin pathway. However,...

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Detalles Bibliográficos
Autores principales: Bordonaro, Michael, Tewari, Shruti, Cicco, Catherine E., Atamna, Wafa, Lazarova, Darina L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207861/
https://www.ncbi.nlm.nih.gov/pubmed/22073312
http://dx.doi.org/10.1371/journal.pone.0027308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207861/
https://www.ncbi.nlm.nih.gov/pubmed/22073312
http://dx.doi.org/10.1371/journal.pone.0027308

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