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LIS1 Regulates Osteoclast Formation and Function through Its Interactions with Dynein/Dynactin and Plekhm1

Microtubule organization and lysosomal secretion are both critical for the activation and function of osteoclasts, highly specialized polykaryons that are responsible for bone resorption and skeletal homeostasis. Here, we have identified a novel interaction between microtubule regulator LIS1 and Ple...

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Detalles Bibliográficos
Autores principales: Ye, Shiqiao, Fowler, Tristan W., Pavlos, Nathan J., Ng, Pei Ying, Liang, Kai, Feng, Yunfeng, Zheng, Minghao, Kurten, Richard, Manolagas, Stavros C., Zhao, Haibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207863/
https://www.ncbi.nlm.nih.gov/pubmed/22073305
http://dx.doi.org/10.1371/journal.pone.0027285