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LIS1 Regulates Osteoclast Formation and Function through Its Interactions with Dynein/Dynactin and Plekhm1
Microtubule organization and lysosomal secretion are both critical for the activation and function of osteoclasts, highly specialized polykaryons that are responsible for bone resorption and skeletal homeostasis. Here, we have identified a novel interaction between microtubule regulator LIS1 and Ple...
Autores principales: | Ye, Shiqiao, Fowler, Tristan W., Pavlos, Nathan J., Ng, Pei Ying, Liang, Kai, Feng, Yunfeng, Zheng, Minghao, Kurten, Richard, Manolagas, Stavros C., Zhao, Haibo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207863/ https://www.ncbi.nlm.nih.gov/pubmed/22073305 http://dx.doi.org/10.1371/journal.pone.0027285 |
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