Foxn1 Regulates Lineage Progression in Cortical and Medullary Thymic Epithelial Cells But Is Dispensable for Medullary Sublineage Divergence

The forkhead transcription factor Foxn1 is indispensable for thymus development, but the mechanisms by which it mediates thymic epithelial cell (TEC) development are poorly understood. To examine the cellular and molecular basis of Foxn1 function, we generated a novel and revertible hypomorphic alle...

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Detalles Bibliográficos
Autores principales: Nowell, Craig S., Bredenkamp, Nicholas, Tetélin, Stéphanie, Jin, Xin, Tischner, Christin, Vaidya, Harsh, Sheridan, Julie M., Stenhouse, Frances Hogg, Heussen, Raphaela, Smith, Andrew J. H., Blackburn, C. Clare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207875/
https://www.ncbi.nlm.nih.gov/pubmed/22072979
http://dx.doi.org/10.1371/journal.pgen.1002348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207875/
https://www.ncbi.nlm.nih.gov/pubmed/22072979
http://dx.doi.org/10.1371/journal.pgen.1002348

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