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Signatures of Environmental Genetic Adaptation Pinpoint Pathogens as the Main Selective Pressure through Human Evolution

Previous genome-wide scans of positive natural selection in humans have identified a number of non-neutrally evolving genes that play important roles in skin pigmentation, metabolism, or immune function. Recent studies have also shown that a genome-wide pattern of local adaptation can be detected by...

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Detalles Bibliográficos
Autores principales: Fumagalli, Matteo, Sironi, Manuela, Pozzoli, Uberto, Ferrer-Admettla, Anna, Pattini, Linda, Nielsen, Rasmus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207877/
https://www.ncbi.nlm.nih.gov/pubmed/22072984
http://dx.doi.org/10.1371/journal.pgen.1002355