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Assessing Predicted HIV-1 Replicative Capacity in a Clinical Setting

HIV-1 replicative capacity (RC) provides a measure of within-host fitness and is determined in the context of phenotypic drug resistance testing. However it is unclear how these in-vitro measurements relate to in-vivo processes. Here we assess RCs in a clinical setting by combining a previously publ...

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Detalles Bibliográficos
Autores principales: Kouyos, Roger D., von Wyl, Viktor, Hinkley, Trevor, Petropoulos, Christos J., Haddad, Mojgan, Whitcomb, Jeannette M., Böni, Jürg, Yerly, Sabine, Cellerai, Cristina, Klimkait, Thomas, Günthard, Huldrych F., Bonhoeffer, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207887/
https://www.ncbi.nlm.nih.gov/pubmed/22072960
http://dx.doi.org/10.1371/journal.ppat.1002321