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A Novel Protein LZTFL1 Regulates Ciliary Trafficking of the BBSome and Smoothened

Many signaling proteins including G protein-coupled receptors localize to primary cilia, regulating cellular processes including differentiation, proliferation, organogenesis, and tumorigenesis. Bardet-Biedl Syndrome (BBS) proteins are involved in maintaining ciliary function by mediating protein tr...

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Detalles Bibliográficos
Autores principales: Seo, Seongjin, Zhang, Qihong, Bugge, Kevin, Breslow, David K., Searby, Charles C., Nachury, Maxence V., Sheffield, Val C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207910/
https://www.ncbi.nlm.nih.gov/pubmed/22072986
http://dx.doi.org/10.1371/journal.pgen.1002358