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A LysM and SH3-Domain Containing Region of the Listeria monocytogenes p60 Protein Stimulates Accessory Cells to Promote Activation of Host NK Cells

Listeria monocytogenes (Lm) infection induces rapid and robust activation of host natural killer (NK) cells. Here we define a region of the abundantly secreted Lm endopeptidase, p60, that potently but indirectly stimulates NK cell activation in vitro and in vivo. Lm expression of p60 resulted in inc...

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Detalles Bibliográficos
Autores principales: Schmidt, Rebecca L., Filak, Holly C., Lemon, Jack D., Potter, Terry A., Lenz, Laurel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207947/
https://www.ncbi.nlm.nih.gov/pubmed/22072975
http://dx.doi.org/10.1371/journal.ppat.1002368