The Statistics of Bulk Segregant Analysis Using Next Generation Sequencing

We describe a statistical framework for QTL mapping using bulk segregant analysis (BSA) based on high throughput, short-read sequencing. Our proposed approach is based on a smoothed version of the standard [Image: see text] statistic, and takes into account variation in allele frequency estimates du...

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Detalles Bibliográficos
Autores principales: Magwene, Paul M., Willis, John H., Kelly, John K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207950/
https://www.ncbi.nlm.nih.gov/pubmed/22072954
http://dx.doi.org/10.1371/journal.pcbi.1002255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207950/
https://www.ncbi.nlm.nih.gov/pubmed/22072954
http://dx.doi.org/10.1371/journal.pcbi.1002255

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