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The Statistics of Bulk Segregant Analysis Using Next Generation Sequencing
We describe a statistical framework for QTL mapping using bulk segregant analysis (BSA) based on high throughput, short-read sequencing. Our proposed approach is based on a smoothed version of the standard [Image: see text] statistic, and takes into account variation in allele frequency estimates du...
Autores principales: | Magwene, Paul M., Willis, John H., Kelly, John K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207950/ https://www.ncbi.nlm.nih.gov/pubmed/22072954 http://dx.doi.org/10.1371/journal.pcbi.1002255 |
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