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Single Molecule Analysis of Replicated DNA Reveals the Usage of Multiple KSHV Genome Regions for Latent Replication

Kaposi's sarcoma associated herpesvirus (KSHV), an etiologic agent of Kaposi's sarcoma, Body Cavity Based Lymphoma and Multicentric Castleman's Disease, establishes lifelong latency in infected cells. The KSHV genome tethers to the host chromosome with the help of a latency associated...

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Detalles Bibliográficos
Autores principales: Verma, Subhash C., Lu, Jie, Cai, Qiliang, Kosiyatrakul, Settapong, McDowell, Maria E., Schildkraut, Carl L., Robertson, Erle S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207954/
https://www.ncbi.nlm.nih.gov/pubmed/22072974
http://dx.doi.org/10.1371/journal.ppat.1002365