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Effects of DNMT1 silencing on malignant phenotype and methylated gene expression in cervical cancer cells

BACKGROUND: DNA methylation has been widely used in classification, early diagnosis, therapy and prediction of metastasis as well as recurrence of cervical cancer. DNMT methyltransferase 1 (DNMT1), which plays a significant role in maintaining DNA methylation status and regulating the expression of...

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Detalles Bibliográficos
Autores principales: Zhang, Yi, Chen, Fu-qiang, Sun, Ye-hong, Zhou, Shu-yan, Li, Ti-yuan, Chen, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207958/
https://www.ncbi.nlm.nih.gov/pubmed/21999220
http://dx.doi.org/10.1186/1756-9966-30-98