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Development of a highly sensitive method for detection of JAK2V617F

BACKGROUND: Ph- myeloproliferative neoplasms (MPNs) represent a heterogeneous group of chronic diseases characterized by increased expansion of hematopoietic cells of the myeloid lineage. JAK2V617F, an activation mutation form of tyrosine kinase JAK2, is found in the majority of patients with MPNs....

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Detalles Bibliográficos
Autores principales: Zhao, Anna H, Gao, Rufei, Zhao, Zhizhuang J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207960/
https://www.ncbi.nlm.nih.gov/pubmed/21985400
http://dx.doi.org/10.1186/1756-8722-4-40