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Overexpression of serine racemase in retina and overproduction of D-serine in eyes of streptozotocin-induced diabetic retinopathy

BACKGROUND: Recent data indicate that inflammatory mechanisms contribute to diabetic retinopathy (DR). We have determined that serine racemase (SR) expression is increased by inflammatory stimuli including liposaccharide (LPS), amyloid β-peptide (A-beta), and secreted amyloid precursor protein (sAPP...

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Detalles Bibliográficos
Autores principales: Jiang, Haiyan, Fang, Junxu, Wu, Bo, Yin, Guibin, Sun, Lin, Qu, Jia, Barger, Steven W, Wu, Shengzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207970/
https://www.ncbi.nlm.nih.gov/pubmed/21939517
http://dx.doi.org/10.1186/1742-2094-8-119