Unbiased Functional Proteomics Strategy for Protein Kinase Inhibitor Validation and Identification of bona fide Protein Kinase Substrates: Application to Identification of EEF1D as a Substrate for CK2

[Image: see text] Protein kinases have emerged as attractive targets for treatment of several diseases prompting large-scale phosphoproteomics studies to elucidate their cellular actions and the design of novel inhibitory compounds. Current limitations include extensive reliance on consensus predict...

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Detalles Bibliográficos
Autores principales: Gyenis, Laszlo, Duncan, James S., Turowec, Jacob P., Bretner, Maria, Litchfield, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208357/
https://www.ncbi.nlm.nih.gov/pubmed/21936567
http://dx.doi.org/10.1021/pr2008994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208357/
https://www.ncbi.nlm.nih.gov/pubmed/21936567
http://dx.doi.org/10.1021/pr2008994

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