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GSTPi-positive tumour microenvironment-associated fibroblasts are significantly associated with GSTPi-negative cancer cells in paired cases of primary invasive breast cancer and axillary lymph node metastases

BACKGROUND: Glutathione S-transferase Pi (GSTPi) expression is one of the factors, which is known to be associated with development of resistance to chemotherapeutics in cancer patients, including those with breast cancer. Yet, its expression has been reported to be undetectable in cancer cells in h...

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Detalles Bibliográficos
Autores principales: Chaiwun, B, Sukhamwang, N, Trakultivakorn, H, Saha, B, Young, L, Tsao-Wei, D, Naritoku, W Y, Groshen, S, Taylor, C R, Imam, S A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208492/
https://www.ncbi.nlm.nih.gov/pubmed/21897388
http://dx.doi.org/10.1038/bjc.2011.352