The role of PARP in DNA repair and its therapeutic exploitation

Historically, PARP inhibitors (PARPi) were developed to potentiate the cytotoxic effect of certain chemotherapeutic agents and are currently being investigated in combination with chemotherapy in diverse cancer types. These agents are also radiosensitisers and clinical trials of PARPi with concurren...

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Detalles Bibliográficos
Autores principales: Javle, M, Curtin, N J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208503/
https://www.ncbi.nlm.nih.gov/pubmed/21989215
http://dx.doi.org/10.1038/bjc.2011.382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208503/
https://www.ncbi.nlm.nih.gov/pubmed/21989215
http://dx.doi.org/10.1038/bjc.2011.382

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