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CCL2 recruits inflammatory monocytes to facilitate breast tumor metastasis

Macrophages abundantly found in the tumor microenvironment enhance malignancy(1). At metastatic sites a distinct population of metastasis associated macrophages (MAMs) promote tumor cell extravasation, seeding and persistent growth(2). Our study has defined the origin of these macrophages by showing...

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Detalles Bibliográficos
Autores principales: Qian, Bin-Zhi, Li, Jiufeng, Zhang, Hui, Kitamura, Takanori, Zhang, Jinghang, Campion, Liam R., Kaiser, Elizabeth A., Snyder, Linda A., Pollard, Jeffrey W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208506/
https://www.ncbi.nlm.nih.gov/pubmed/21654748
http://dx.doi.org/10.1038/nature10138