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Revisiting the NMR Structure of the Ultrafast Downhill Folding Protein gpW from Bacteriophage λ

GpW is a 68-residue protein from bacteriophage λ that participates in virus head morphogenesis. Previous NMR studies revealed a novel α+β fold for this protein. Recent experiments have shown that gpW folds in microseconds by crossing a marginal free energy barrier (i.e., downhill folding). These fea...

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Detalles Bibliográficos
Autores principales: Sborgi, Lorenzo, Verma, Abhinav, Muñoz, Victor, de Alba, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208555/
https://www.ncbi.nlm.nih.gov/pubmed/22087227
http://dx.doi.org/10.1371/journal.pone.0026409