Stepwise Maturation of Lytic Granules during Differentiation and Activation of Human CD8(+) T Lymphocytes

During differentiation, cytotoxic T lymphocytes (CTL) acquire their killing potential through the biogenesis and maturation of lytic granules that are secreted upon target cell recognition. How lytic granule load in lytic molecules evolves during CTL differentiation and which subsets of lytic granul...

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Detalles Bibliográficos
Autores principales: Sanchez-Ruiz, Yovan, Valitutti, Salvatore, Dupre, Loic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208563/
https://www.ncbi.nlm.nih.gov/pubmed/22073254
http://dx.doi.org/10.1371/journal.pone.0027057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208563/
https://www.ncbi.nlm.nih.gov/pubmed/22073254
http://dx.doi.org/10.1371/journal.pone.0027057

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