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Integrated Transcriptome and Binding Sites Analysis Implicates E2F in the Regulation of Self-Renewal in Human Pluripotent Stem Cells

Rapid cellular growth and multiplication, limited replicative senescence, calibrated sensitivity to apoptosis, and a capacity to differentiate into almost any cell type are major properties that underline the self-renewal capabilities of human pluripotent stem cells (hPSCs). We developed an integrat...

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Detalles Bibliográficos
Autores principales: Yeo, Hock Chuan, Beh, Thian Thian, Quek, Jovina Jia Ling, Koh, Geoffrey, Chan, Ken Kwok Keung, Lee, Dong-Yup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208628/
https://www.ncbi.nlm.nih.gov/pubmed/22076139
http://dx.doi.org/10.1371/journal.pone.0027231