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Integrated Transcriptome and Binding Sites Analysis Implicates E2F in the Regulation of Self-Renewal in Human Pluripotent Stem Cells
Rapid cellular growth and multiplication, limited replicative senescence, calibrated sensitivity to apoptosis, and a capacity to differentiate into almost any cell type are major properties that underline the self-renewal capabilities of human pluripotent stem cells (hPSCs). We developed an integrat...
Autores principales: | Yeo, Hock Chuan, Beh, Thian Thian, Quek, Jovina Jia Ling, Koh, Geoffrey, Chan, Ken Kwok Keung, Lee, Dong-Yup |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208628/ https://www.ncbi.nlm.nih.gov/pubmed/22076139 http://dx.doi.org/10.1371/journal.pone.0027231 |
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