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Study of Sylvilagus rabbit TRIM5α species-specific domain: how ancient endoviruses could have shaped the antiviral repertoire in Lagomorpha

BACKGROUND: Since the first report of the antiretroviral restriction factor TRIM5α in primates, several orthologs in other mammals have been described. Recent studies suggest that leporid retroviruses like RELIK, the first reported endogenous lentivirus ever, may have imposed positive selection in T...

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Detalles Bibliográficos
Autores principales: de Matos, Ana Lemos, van der Loo, Wessel, Areal, Helena, Lanning, Dennis K, Esteves, Pedro J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208668/
https://www.ncbi.nlm.nih.gov/pubmed/21982459
http://dx.doi.org/10.1186/1471-2148-11-294