Novel Toll-like receptor-4 deficiency attenuates trastuzumab (Herceptin) induced cardiac injury in mice

BACKGROUND: Cardiac inflammation and generation of oxidative stress are known to contribute to trastuzumab (herceptin) induced cardiac toxicity. Toll-like receptors (TLRs) are a part of the innate immune system and are involved in cardiac stress reactions. Since TLR4 might play a relevant role in ca...

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Detalles Bibliográficos
Autores principales: Yousif, Nasser Ghaly, Al-amran, Fadhil G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209438/
https://www.ncbi.nlm.nih.gov/pubmed/21999911
http://dx.doi.org/10.1186/1471-2261-11-62

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209438/
https://www.ncbi.nlm.nih.gov/pubmed/21999911
http://dx.doi.org/10.1186/1471-2261-11-62

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