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Derivation of haploid embryonic stem cells from mouse embryos
Most animals are diploid but haploid-only and male-haplo species have been described (1). Diploid genomes of complex organisms limit genetic approaches in biomedical model species such as in mice. To overcome this problem experimental induction of haploidy has been used in fish (2,3). In contrast, h...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209452/ https://www.ncbi.nlm.nih.gov/pubmed/21900896 http://dx.doi.org/10.1038/nature10448 |