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Crosstalk between Nodal/Activin and MAPK p38 Signaling Is Essential for Anterior-Posterior Axis Specification

Nodal/activin signaling plays a key role in anterior-posterior (A-P) axis formation by inducing the anterior visceral endoderm (AVE), the extraembryonic signaling center that initiates anterior patterning in the embryo. Here we provide direct evidence that the mitogen-activated protein kinase (MAPK)...

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Detalles Bibliográficos
Autores principales: Clements, Melanie, Pernaute, Barbara, Vella, Francis, Rodriguez, Tristan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209556/
https://www.ncbi.nlm.nih.gov/pubmed/21802298
http://dx.doi.org/10.1016/j.cub.2011.06.048