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Abca12-mediated lipid transport and Snap29-dependent trafficking of lamellar granules are crucial for epidermal morphogenesis in a zebrafish model of ichthyosis

Zebrafish (Danio rerio) can serve as a model system to study heritable skin diseases. The skin is rapidly developed during the first 5–6 days of embryonic growth, accompanied by expression of skin-specific genes. Transmission electron microscopy (TEM) of wild-type zebrafish at day 5 reveals a two-ce...

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Detalles Bibliográficos
Autores principales: Li, Qiaoli, Frank, Michael, Akiyama, Masashi, Shimizu, Hiroshi, Ho, Shiu-Ying, Thisse, Christine, Thisse, Bernard, Sprecher, Eli, Uitto, Jouni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209647/
https://www.ncbi.nlm.nih.gov/pubmed/21816950
http://dx.doi.org/10.1242/dmm.007146