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Abca12-mediated lipid transport and Snap29-dependent trafficking of lamellar granules are crucial for epidermal morphogenesis in a zebrafish model of ichthyosis
Zebrafish (Danio rerio) can serve as a model system to study heritable skin diseases. The skin is rapidly developed during the first 5–6 days of embryonic growth, accompanied by expression of skin-specific genes. Transmission electron microscopy (TEM) of wild-type zebrafish at day 5 reveals a two-ce...
Autores principales: | Li, Qiaoli, Frank, Michael, Akiyama, Masashi, Shimizu, Hiroshi, Ho, Shiu-Ying, Thisse, Christine, Thisse, Bernard, Sprecher, Eli, Uitto, Jouni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Limited
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209647/ https://www.ncbi.nlm.nih.gov/pubmed/21816950 http://dx.doi.org/10.1242/dmm.007146 |
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