A high level of liver-specific expression of oncogenic Kras(V12) drives robust liver tumorigenesis in transgenic zebrafish

Human liver cancer is one of the deadliest cancers worldwide, with hepatocellular carcinoma (HCC) being the most common type. Aberrant Ras signaling has been implicated in the development and progression of human HCC, but a complete understanding of the molecular mechanisms of this protein in hepato...

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Detalles Bibliográficos
Autores principales: Nguyen, Anh Tuan, Emelyanov, Alexander, Koh, Chor Hui Vivien, Spitsbergen, Jan M., Lam, Siew Hong, Mathavan, Sinnakaruppan, Parinov, Serguei, Gong, Zhiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209649/
https://www.ncbi.nlm.nih.gov/pubmed/21729876
http://dx.doi.org/10.1242/dmm.007831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209649/
https://www.ncbi.nlm.nih.gov/pubmed/21729876
http://dx.doi.org/10.1242/dmm.007831

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