A Sequence-Specific Threading Tetraintercalator with an Extremely Slow Dissociation Rate Constant

A long-lived and sequence specific ligand-DNA complex would make possible the modulation of biological processes for extended periods. We have been investigating the threading polyintercalation approach to DNA recognition in which chains of aromatic units thread back and forth repeatedly through the...

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Detalles Bibliográficos
Autores principales: Holman, Garen G., Zewail-Foote, Maha, Smith, Amy Rhoden, Johnson, Kenneth A., Iverson, Brent L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209807/
https://www.ncbi.nlm.nih.gov/pubmed/22024884
http://dx.doi.org/10.1038/nchem.1151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209807/
https://www.ncbi.nlm.nih.gov/pubmed/22024884
http://dx.doi.org/10.1038/nchem.1151

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