Cargando…

Improving the Estimation of Celiac Disease Sibling Risk by Non-HLA Genes

Celiac Disease (CD) is a polygenic trait, and HLA genes explain less than half of the genetic variation. Through large GWAs more than 40 associated non-HLA genes were identified, but they give a small contribution to the heritability of the disease. The aim of this study is to improve the estimate o...

Descripción completa

Detalles Bibliográficos
Autores principales: Izzo, Valentina, Pinelli, Michele, Tinto, Nadia, Esposito, Maria Valeria, Cola, Arturo, Sperandeo, Maria Pia, Tucci, Francesca, Cocozza, Sergio, Greco, Luigi, Sacchetti, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210127/
https://www.ncbi.nlm.nih.gov/pubmed/22087237
http://dx.doi.org/10.1371/journal.pone.0026920