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Gene Expression-Based Chemical Genomics Identifies Potential Therapeutic Drugs in Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is an aggressive tumor with a poor prognosis. Currently, only sorafenib is approved by the FDA for advanced HCC treatment; therefore, there is an urgent need to discover candidate therapeutic drugs for HCC. We hypothesized that if a drug signature could reverse, at lea...

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Detalles Bibliográficos
Autores principales: Chen, Ming-Huang, Yang, Wu-Lung R., Lin, Kuan-Ting, Liu, Chia-Hung, Liu, Yu-Wen, Huang, Kai-Wen, Chang, Peter Mu-Hsin, Lai, Jin-Mei, Hsu, Chun-Nan, Chao, Kun-Mao, Kao, Cheng-Yan, Huang, Chi-Ying F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210146/
https://www.ncbi.nlm.nih.gov/pubmed/22087264
http://dx.doi.org/10.1371/journal.pone.0027186