Cargando…
Gene Expression-Based Chemical Genomics Identifies Potential Therapeutic Drugs in Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is an aggressive tumor with a poor prognosis. Currently, only sorafenib is approved by the FDA for advanced HCC treatment; therefore, there is an urgent need to discover candidate therapeutic drugs for HCC. We hypothesized that if a drug signature could reverse, at lea...
Autores principales: | Chen, Ming-Huang, Yang, Wu-Lung R., Lin, Kuan-Ting, Liu, Chia-Hung, Liu, Yu-Wen, Huang, Kai-Wen, Chang, Peter Mu-Hsin, Lai, Jin-Mei, Hsu, Chun-Nan, Chao, Kun-Mao, Kao, Cheng-Yan, Huang, Chi-Ying F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210146/ https://www.ncbi.nlm.nih.gov/pubmed/22087264 http://dx.doi.org/10.1371/journal.pone.0027186 |
Ejemplares similares
-
Detection of the inferred interaction network in hepatocellular carcinoma from EHCO (Encyclopedia of Hepatocellular Carcinoma genes Online)
por: Hsu, Chun-Nan, et al.
Publicado: (2007) -
In silico identification of thiostrepton as an inhibitor of cancer stem cell growth and an enhancer for chemotherapy in non–small‐cell lung cancer
por: Huang, Tse‐Hung, et al.
Publicado: (2019) -
Whole-Exome Sequencing to Identify a Novel LMNA Gene Mutation Associated with Inherited Cardiac Conduction Disease
por: Lai, Chun-Chi, et al.
Publicado: (2013) -
In silico drug screening and potential target identification for hepatocellular carcinoma using support vector machine
por: Yang, Wu-Lung R, et al.
Publicado: (2012) -
Characterization of a novel androgen receptor (AR) coregulator RIPK1 and related chemicals that suppress AR-mediated prostate cancer growth via peptide and chemical screening
por: Hsu, Cheng-Lung, et al.
Publicado: (2017)