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Free Fatty Acid-Induced PP2A Hyperactivity Selectively Impairs Hepatic Insulin Action on Glucose Metabolism

In type 2 Diabetes (T2D) free fatty acids (FFAs) in plasma are increased and hepatic insulin resistance is “selective”, in the sense that the insulin-mediated decrease of glucose production is blunted while insulin's effect on stimulating lipogenesis is maintained. We investigated the molecular...

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Detalles Bibliográficos
Autores principales: Galbo, Thomas, Olsen, Grith Skytte, Quistorff, Bjørn, Nishimura, Erica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210172/
https://www.ncbi.nlm.nih.gov/pubmed/22087313
http://dx.doi.org/10.1371/journal.pone.0027424