Cargando…
Free Fatty Acid-Induced PP2A Hyperactivity Selectively Impairs Hepatic Insulin Action on Glucose Metabolism
In type 2 Diabetes (T2D) free fatty acids (FFAs) in plasma are increased and hepatic insulin resistance is “selective”, in the sense that the insulin-mediated decrease of glucose production is blunted while insulin's effect on stimulating lipogenesis is maintained. We investigated the molecular...
Autores principales: | Galbo, Thomas, Olsen, Grith Skytte, Quistorff, Bjørn, Nishimura, Erica |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210172/ https://www.ncbi.nlm.nih.gov/pubmed/22087313 http://dx.doi.org/10.1371/journal.pone.0027424 |
Ejemplares similares
-
PP2A inhibition results in hepatic insulin resistance despite Akt2 activation
por: Galbo, Thomas, et al.
Publicado: (2013) -
Adipose Weight Gain during Chronic Insulin Treatment of Mice Results from Changes in Lipid Storage without Affecting De Novo Synthesis of Palmitate
por: Frikke-Schmidt, Henriette, et al.
Publicado: (2013) -
Insulin Action, Glucose Homeostasis and Free Fatty Acid Metabolism: Insights From a Novel Model
por: Stefanovski, Darko, et al.
Publicado: (2021) -
Corrigendum: Insulin Action, Glucose Homeostasis and Free Fatty Acid Metabolism: Insights From a Novel Model
por: Stefanovski, Darko, et al.
Publicado: (2021) -
Free fatty acids, glucose, and insulin in type 2 diabetes mellitus
por: Weijers, Rob NM
Publicado: (2022)