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Novel Common Integration Sites Targeted by Mouse Mammary Tumor Virus Insertion in Mammary Tumors Have Oncogenic Activity

Non-acute transforming retroviruses like mouse mammary tumor virus (MMTV) cause cancer, at least in part, through integration near cellular genes involved in growth control, thereby de-regulating their expression. It is well-established that MMTV commonly integrates near and activates expression of...

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Detalles Bibliográficos
Autores principales: Kim, Hyoung H., van den Heuvel, A. Pieter J., Schmidt, John W., Ross, Susan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210173/
https://www.ncbi.nlm.nih.gov/pubmed/22087314
http://dx.doi.org/10.1371/journal.pone.0027425